drugset / Trial / NCT03346317

Comparing the Efficacy of Two Methods in the Prevention of Adhesion Reformation After Hysteroscopic Adhesiolysis

NCT03346317

RandomizedParallel-groupDouble-blindPrevention

Summary

Asherman's syndrome is characterized by the presence of intrauterine adhesions (IUA) as well as symptoms such as amenorrhea, hypomenorrhea, pelvic pain, and infertility. The gold standard for the treatment of intrauterine adhesions is hysteroscopic intrauterine adhesions. The recurrence of intrauterine adhesions is a major challenge in clinical practice. It has been reported that dried biological aminion graft was used to prevent adhesion after the operation of intrauterine adhesions. Estrogen is also used for postoperative prevention of intrauterine adhesions. Intrauterine balloon can reduce the recurrence of adhesions after operation. Does the combination of balloon with amniotic products or estrogen can improve clinical outcomes? Therefore, this study was conducted.

Timeline

Start
2017-11-16
Primary completion
2018-05-16
Completion
2018-05-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Dydrogesterone Other / unclassified Oral
Subject estradiol valerate Unknown Oral

Indications