[18F]-F13640 as a New Brain Radiopharmaceutical

Summary

This clinical assay is designed to validate that \[18F\]F13640 as a radiotracer of 5-HT1A functional receptors. A first group of healthy subjects underwent a PET scan with arterial blood sampling to determine the kinetic model of the tracer. A second group of healthy subjects underwent a classical test-retest study (i.e two distant PET scans) to determine the reproducibility of measures.

Timeline

Start

2018-04-23

Primary completion

2021-04-23

Completion

2021-12-02

Publications

• Results Colom M, Costes N, Redoute J, Dailler F, Gobert F, Le Bars D, Billard T, Newman-Tancredi A, Zimmer L. 18F-F13640 PET imaging of functional receptors in humans. Eur J Nucl Med Mol Imaging. 2020 Jan;47(1):220-221. doi: 10.1007/s00259-019-04473-7. Epub 2019 Aug 14. No abstract available.

Drugs

Indications