drugset / Trial / NCT03347513
Eradication of H-pylori in Pregnancy and Its Effect on Iron Replacement Therapy?
RandomizedParallel-groupOpen-labelTreatment
Summary
the effect of eradication of H-pylori in pregnant patients with iron deficiency anemia on the level of hemoglobin after iron therapy.
Timeline
- Start
- 2017-11-25
- Primary completion
- 2019-03
- Completion
- 2019-05
Publications
- Background Nashaat EH, Mansour GM. Helicobacter pylori and anemia with pregnancy. Arch Gynecol Obstet. 2014 Jun;289(6):1197-202. doi: 10.1007/s00404-013-3138-8. Epub 2013 Dec 28.
- Background Breymann C, Honegger C, Hosli I, Surbek D. Diagnosis and treatment of iron-deficiency anaemia in pregnancy and postpartum. Arch Gynecol Obstet. 2017 Dec;296(6):1229-1234. doi: 10.1007/s00404-017-4526-2. Epub 2017 Sep 22.
- Background Chey WD, Leontiadis GI, Howden CW, Moss SF. ACG Clinical Guideline: Treatment of Helicobacter pylori Infection. Am J Gastroenterol. 2017 Feb;112(2):212-239. doi: 10.1038/ajg.2016.563. Epub 2017 Jan 10.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Clarithromycin | Small molecule | 500 mg | — |
| Subject | Metronidazole | Small molecule | 500 mg | — |
| Subject | Omeprazole | Other / unclassified | 20 mg | — |
| Background | ferrous(II)-glycine-sulphate complex | Unknown | 567.7 mg | — |