drugset / Trial / NCT03350906
Enhancing Adaptations to Exercise
Phase 3
Completed
63 enrolled
Mayo Clinic
National Center for Research Resources (NCRR) · collabNational Institute on Aging (NIA) · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
Researchers are trying to understand how chronic inflammation affects muscle function and responses to exercise.They are also trying to determine if suppressing chronic inflammation using omega-3 fatty acids (n3-PUFA) restores skeletal muscle function and exercise responsiveness in older adults.
Timeline
- Start
- 2018-01-01
- Primary completion
- 2021-12-31
- Completion
- 2021-12-31
Publications
- Moosavi D, Vuckovic I, Kunz HE, Lanza IR. Metabolomic response to acute resistance exercise in healthy older adults by 1H-NMR. PLoS One. 2024 Mar 28;19(3):e0301037. doi: 10.1371/journal.pone.0301037. eCollection 2024.
- Moosavi D, Vuckovic I, Kunz HE, Lanza IR. A Randomized Trial of omega-3 Fatty Acid Supplementation and Circulating Lipoprotein Subclasses in Healthy Older Adults. J Nutr. 2022 Jul 6;152(7):1675-1689. doi: 10.1093/jn/nxac084.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | n-3 polyunsaturated fatty acids | Other / unclassified | 3.4 g | Oral |
Indications
No indication recorded.