drugset / Trial / NCT03351439

Efficacy of Multimodal Analgesia Following Hip Arthroscopy

NCT03351439

Completed 100 enrolled Western University, Canada
RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of the full study is to determine whether multimodal analgesia for hip arthroscopy will reduce post-operative pain scores, narcotic consumption and hospital length-of-stay. To do this, the investigators will compare the standard of care (SOC), with routine pain management with a post-operative opioid prescription, to three different groups with multi-modal analgesia (SOC+peri-operative celecoxib, SOC+peri-operative gabapentin, and SOC+post-operative zopiclone). The investigators hypothesize that administration of multi-modal analgesia in all three treatment groups will result in improved post-operative pain control, reduced post-operative narcotic consumption and an overall reduction in post-operative length-of-stay compared to the group receiving treatment as per the standard of care. However, prior to undertaking a large multi-centre study, the investigators need to determine whether the study is feasible from data obtained with this pilot study.

Timeline

Start
2018-04-06
Primary completion
2021-09-30
Completion
2021-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Celecoxib Other / unclassified 400 mg Oral
Subject Gabapentin Small molecule 600 mg Oral
Subject Zopiclone Small molecule 7.5 mg Oral
Background Naproxen Small molecule 500 mg
Background Oxycodone Other / unclassified 5 mg
Background Oxycodone Other / unclassified 325 mg

Indications