drugset / Trial / NCT03356080

DLAAG in the Treatment of Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome With Blast Excess

NCT03356080

Phase 2 Unknown 50 enrolled Shanghai Tong Ren Hospital
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate of the clinical efficacy and safety of DLAAG protocol in the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome with blast excess

Timeline

Start
2017-07-07
Primary completion
2019-07-07
Completion
2020-07-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Cytarabine Small molecule 15 mg/m2 Intravenous
Subject Decitabine Small molecule 0.1 mg/kg Intravenous
Subject Decitabine Small molecule 0.2 mg/kg Intravenous
Subject Tretinoin Small molecule 15 mg
Background G-CSF Unknown 300 ug Subcutaneous