drugset / Trial / NCT03356457
Development of Agents to Diminish the Risk of Hypoglycemia-induced Brain Injury in Type 1 Diabetes
RandomizedCrossoverSingle-blindTreatment
Summary
To determine the effect of re-activation of brain glucose metabolism induced by dichloroacetate (DCA) on cognitive function and counterregulatory hormone responses in patients with type 1 diabetes (T1DM) with recurrent hypoglycemia.
Timeline
- Start
- 2017-11-30
- Primary completion
- 2019-03-20
- Completion
- 2019-03-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dichloroacetate | Small molecule | 12.5 mg/kg | — |