drugset / Trial / NCT03356782

Safety and Efficacy Evaluation of 4th Generation Safety-engineered CAR T Cells Targeting Sarcomas

NCT03356782 ↗

Phase 1/2 Recruiting 20 enrolled Shenzhen Geno-Immune Medical Institute
NaSingle-groupOpen-labelTreatment

Summary

The aim of this clinical trial is to assess the feasibility, safety and efficacy of CAR T cells immunotherapy in patients who have sarcoma that is relapsed or late staged. Another goal of the study is to assess the safety and efficacy of the therapy that combines CAR T cells and IgT cells to treat sarcoma.

Timeline

Start
2026-06-01
Primary completion
2029-12-31
Completion
2030-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Sarcoma-specific CAR-T cells Cell therapy 1e+06 cells/kg Intravenous
Subject Sarcoma-specific CAR-T cells Cell therapy 1e+07 cells/kg Intravenous