drugset / Trial / NCT03359174

An Efficacy Trial of Low Dose All-trans Retinoic Acid in Patients With Primary Sclerosing Cholangitis

NCT03359174

Phase 2 Terminated 2 enrolled Yale University
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this research study is to determine whether a low dose of ATRA will improve laboratory tests of liver and bile duct inflammation in patients with PSC. The investigators will also look for changes to other blood tests which are related to inflammation, scarring, and the immune system.

Timeline

Start
2018-05-29
Primary completion
2020-12-01
Completion
2021-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Tretinoin Small molecule 10 mg