drugset / Trial / NCT03359291
Clinical Study to Investigate the Effect of Macitentan on the Concentrations of Rosuvastatin in the Blood of Healthy Male Subjects
NaSingle-groupOpen-labelOther
Summary
The aim of this Phase 1 trial is to study a potential drug-drug interaction between macitentan and rosuvastatin, a model substrate of various transporter proteins (e.g. in the gut).
Timeline
- Start
- 2017-11-03
- Primary completion
- 2017-12-04
- Completion
- 2017-12-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Macitentan | Other / unclassified | 10 mg | Oral |
| Subject | Rosuvastatin | Small molecule | 10 mg | Oral |
Indications
No indication recorded.