drugset / Trial / NCT03370159

CPI-613 and Docetaxel in Treating Patients With Stage IIIB or IV Non-small Cell Lung Cancer

NCT03370159

NaSingle-groupOpen-labelTreatment

Summary

This phase I/II trial studies the side effects and best dose of 6,8-bis(benzylthio)octanoic acid (CPI-613) when given together with docetaxel and to see how well they work in treating patients with stage IIIB or IV non-small cell lung cancer. Drugs used in chemotherapy, such as CPI-613 and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

Timeline

Start
2018-06
Primary completion
2019-03-01
Completion
2020-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject CPI-613 Small molecule Intravenous
Subject Docetaxel Small molecule Intravenous