drugset / Trial / NCT03371979
Pegzilarginase and Pembrolizumab for Extensive Disease Small Cell Lung Cancer
NaSingle-groupOpen-labelTreatment
Summary
The main purpose of this Phase 1/2 study is to determine the safety and efficacy of pegzilarginase in combination with pembrolizumab in patients with ED-SCLC who have relapsed or progressive disease on or within 6 months of platinum-based chemotherapy.
Timeline
- Start
- 2017-12-21
- Primary completion
- 2021-01-01
- Completion
- 2021-01-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Pegzilarginase | Protein / enzyme biologic | — | Intravenous |
| Background | Pembrolizumab | Monoclonal antibody | — | Intravenous |