drugset / Trial / NCT03375515

PCA vs Non-PCA Intravenous Hydromorphone Titration for Severe Cancer Pain

NCT03375515

Phase 3 Completed 214 enrolled Fujian Cancer Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

A large number of studies have shown that patients feel more satisfied with hydromorphone in the pain management. and a systematic review found that hydromorphone may be better suited than morphine for titration of acute analgesia. However, current researches on intravenous opioid titration for cancer pain such as hydromorphone are relatively insufficient in China. Therefore, a prospective, multi-center, randomized controlled study is conducted to assess the efficacy and safety of comparing patient-controlled analgesia (PCA) versus non-PCA intravenous hydromorphone titration for severe cancer pain.

Timeline

Start
2018-09-29
Primary completion
2019-12-10
Completion
2020-01-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Hydromorphone Other / unclassified 0.5 mg Intravenous
Subject Hydromorphone Other / unclassified 10 % Intravenous

Indications

No indication recorded.