drugset / Trial / NCT03375697

A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-63733657 in Healthy Subjects and Subjects With Alzheimer's Disease

NCT03375697 ↗

Phase 1 Completed 72 enrolled Janssen Research & Development, LLC
RandomizedSequentialDouble-blindTreatment

Summary

The purpose of this study is to assess the safety and tolerability of JNJ-63733657 following single ascending intravenous (IV) dose administration in healthy subjects (Part 1) and multiple ascending IV dose administrations in subjects with prodromal or mild Alzheimer's disease (AD) (Part 2).

Timeline

Start
2017-12-22
Primary completion
2019-12-16
Completion
2019-12-16

Drugs

EvaluationDrugModalityDoseRoute
Subject posdinemab Monoclonal antibody — Intravenous

Indications