drugset / Trial / NCT03376841

Impact of Severe Hepatic Impairment on Pharmacokinetics of Cenicriviroc and Its Metabolites

NCT03376841

Phase 1 Completed 16 enrolled Allergan
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The objective of this study is to assess the pharmacokinetics (PK), safety, and tolerability profiles of cenicriviroc (CVC) and its metabolites (M-I and M-II) in participants with severely impaired hepatic function compared with matched healthy participants following single-dose administration

Timeline

Start
2017-06-06
Primary completion
2017-11-24
Completion
2017-12-17

Drugs

EvaluationDrugModalityDoseRoute
Subject Cenicriviroc Small molecule Oral