Allopurinol and Endothelial Function in Diabetic CAD Patients

Summary

This is a randomized trial assessing the impact of allopurinol on endothelial function in optimally treated diabetic patients with coronary artery disease. After initial screening, subjects were randomized to receive either optimal medical therapy (OMT) + allopurinol or OMT alone for 8 weeks. The dose of allopurinol was 300 mg for 4 weeks and 600 mg for 4 weeks with a 4-weekly check on hematology and biochemistry

Timeline

Start

2017-12

Primary completion

2018-03

Completion

2018-06

Drugs

Indications