drugset / Trial / NCT03385486

Study of TBX-3400 in Patients With Stage III and IV Melanoma Resistant or Refractory to Immune Checkpoint Inhibitors

NCT03385486 ↗

Phase 1 Unknown 72 enrolled Taiga Biotechnologies, Inc.
NaSequentialOpen-labelTreatment

Summary

This is a study of transfusion of TBX-3400 in patients with stage III and IV melanoma resistant or refractory to Immune Checkpoint Inhibitors. The patient's own blood cells are exposed to a protein that has been shown in the laboratory to result in anti-tumor activity. The study hypothesis is that TBX-3400 cells will enhance anti-tumor activity and improve the body's immune response.

Timeline

Start
2019-06-02
Primary completion
2023-02
Completion
2024-12

Drugs

EvaluationDrugModalityDoseRoute
Subject TBX-3400 Cell therapy — Intravenous

Indications