DOT Diary Optimization Pilot: A Pilot Study to Optimize the DOT Diary App to Measure PrEP Adherence

Phase 4 Completed 20 enrolled Public Health Foundation Enterprises, Inc. AiCure · collab Emory University · collab National Institute of Mental Health (NIMH) · collab San Francisco Department of Public Health · collab

NaSingle-groupOpen-labelOther

Summary

The researchers are working with a technology company, AiCure, to develop a smartphone app, DOT Diary, which combines two drug adherence strategies. DOT Diary reminds people when it is time to take their medication, and uses motion-sensing technology to visually and automatically confirm the pill was swallowed. The goal of this study is to understand people's experiences using this new app while taking HIV pre-exposure prophylaxis (PrEP) for the prevention of HIV.

Timeline

Start: 2018-02-28
Primary completion: 2018-08-30
Completion: 2018-08-30

Publications

Results Liu AY, Laborde ND, Coleman K, Vittinghoff E, Gonzalez R, Wilde G, Thorne AL, Ikeguchi E, Shafner L, Sunshine L, van der Straten A, Siegler AJ, Buchbinder S. DOT Diary: Developing a Novel Mobile App Using Artificial Intelligence and an Electronic Sexual Diary to Measure and Support PrEP Adherence Among Young Men Who Have Sex with Men. AIDS Behav. 2021 Apr;25(4):1001-1012. doi: 10.1007/s10461-020-03054-2. Epub 2020 Oct 12.

Drugs

Evaluation	Drug	Modality	Dose	Route
Background	Tenofovir disoproxil fumarate	Small molecule	—	Oral
Background	emtricitabine	Other / unclassified	—	Oral

Indications

No indication recorded.