drugset / Trial / NCT03390426
Femoral Peri-arterial Local Anesthetic Injection Decreases Tourniquet Associated Ischemic Hypertension
RandomizedParallel-groupDouble-blindSupportive care
Summary
The purpose of this prospective randomized double-blind study is to determine if the novel technique of ultrasound guided peri-arterial injection of local anesthetic around the femoral artery decreases ischemic hypertension associated with prolonged lower extremity tourniquet time during total ankle arthroplasty (TAA) and foot fusion surgeries. Patients will be randomized 1:1 to receive either local anesthetic or saline, which will be injected superomedially to the femoral artery in an attempt to block sympathetic afferents and decrease tourniquet associated hypertension intraoperatively.
Timeline
- Start
- 2018-05-03
- Primary completion
- 2018-10-27
- Completion
- 2018-10-28
Outcome
Met primary endpoint
paper TH was present in 93.3% of sham patients versus 33.3% of block patients. PMID 33431616 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Mepivacaine | Other / unclassified | 1.5 % | Other |
| Subject | Mepivacaine | Other / unclassified | 15 ml | Other |
Indications
No indication recorded.