drugset / Trial / NCT03391765

An Extension Study of ABBV-8E12 in Progressive Supranuclear Palsy (PSP)

NCT03391765 ↗

Phase 2 Terminated 142 enrolled AbbVie
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study was to assess the long-term safety and efficacy of ABBV-8E12 (tilavonemab) in participants with progressive supranuclear palsy (PSP).

Timeline

Start
2018-01-24
Primary completion
2019-12-13
Completion
2019-12-13

Outcome

Outcome not reported

Stopped: “This study was prematurely discontinued because the program for progressive supranuclear palsy was discontinued due to lack of efficacy.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Tilavonemab Monoclonal antibody 2000 mg Intravenous
Subject Tilavonemab Monoclonal antibody 4000 mg Intravenous