drugset / Trial / NCT03393728

Heart Rate Variability and Hyperthyroidism: Evaluation of the Short-term Effects of Propanolol

NCT03393728

Phase 4 Completed 10 enrolled Yaounde Central Hospital
NaSingle-groupOpen-labelTreatment

Summary

Objective: The aim of our study was to evaluate the short term effects of Propanolol on heart rate variability in patients with hyperthyroidism. Design: In ten patients newly diagnosed as having hyperthyroidism and naïve of all treatment specific for hyperthyroidism, we evaluated the short term effects of Propanolol on heart rate variability (HRV). Methods: We measured heart rate variability by power spectral analysis during 2 hours of rest and during Ewing's tests before and after the administration of Propanolol 40mg/12 hours orally for 72 hours.

Timeline

Start
2008-09-01
Primary completion
2008-12-30
Completion
2009-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Propranolol Small molecule 40 mg Oral

Indications