Combination of Immunotherapy and Hyperthermia in Advanced Malignant Mesothelioma

Summary

The purpose of this study is to investigate the clinical efficacy and toxicity of anti-PD-1 monoclonal antibody plus autologous dendritic cells-cytokine induced killer cell (DC-CIK) immunotherapy combined with hyperthermia in advanced malignant mesothelioma patients.Furthermore,to characterize response to therapy,the investigators intent to explore the predictive biomarker for this regimen.

Timeline

Start

2017-12-01

Primary completion

2021-12-31

Completion

2022-06-30

Drugs

Indications