Treatment of Early Phase Achilles Tendinopathy - the Effect of NSAIDs

Summary

this study evaluates the addition of initial short term NSAID treatment to physiotherapy prescribed exercise treatment in patient with early phase tendinopathy. Half of the participants will initially receive NSAID (naproxen) for 7 days, while the other half will receive a placebo, where after both groups will be subjected to 3 months heavy slow resistance training.

Timeline

Start

2018-01-15

Primary completion

2019-07-31

Completion

2020-04-27

Outcome

Missed primary endpoint

paper No significant differences were found between the 2 treatment groups for any of the outcome measures at any time point (P > .05). PMID 33719579 ↗

Publications

• Malmgaard-Clausen NM, Jorgensen OH, Hoffner R, Andersen PEB, Svensson RB, Hansen P, Nybing JD, Magnusson SP, Kjaer M. No Additive Clinical or Physiological Effects of Short-term Anti-inflammatory Treatment to Physical Rehabilitation in the Early Phase of Human Achilles Tendinopathy: A Randomized Controlled Trial. Am J Sports Med. 2021 Jun;49(7):1711-1720. doi: 10.1177/0363546521991903. Epub 2021 Mar 15.

Drugs

Indications