drugset / Trial / NCT03402880

ALCMI-005: Pembrolizumab and Epacadostat in Treating Patients With Extensive Stage Small Cell Lung Cancer

NCT03402880

NaSingle-groupOpen-labelTreatment

Summary

This phase II trial studies how well pembrolizumab and epacadostat work in combination treating patients with extensive stage small cell lung cancer. Monoclonal antibodies, such as pembrolizumab, may assist the immune system in recognizing cancer cells leading to elimination of those cells. Epacadostat may prevent down-regulation of T-cells, which means it can boost the immune system. Giving pembrolizumab and epacadostat together may work better than either drug alone in treating extensive stage small cell lung cancer.

Timeline

Start
2018-10
Primary completion
2018-10-03
Completion
2018-10-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Epacadostat Small molecule Oral
Subject Pembrolizumab Monoclonal antibody Intravenous