drugset / Trial / NCT03403348

A First-In-Human Study of Orally Administered JNJ-64417184 to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses, and the Antiviral Activity of Multiple Doses in a Respiratory Syncytial Virus (RSV) Challenge Study in Healthy Participants

NCT03403348

Phase 1 Completed 130 enrolled Janssen BioPharma, Inc.
RandomizedSequentialDouble-blindTreatment

Summary

The purpose of the study is to evaluate the safety and tolerability of single and multiple oral doses of JNJ-64417184 administered to healthy participants and the antiviral effect of multiple oral doses of JNJ-64417184 compared to placebo in participants infected through inoculation with respiratory syncytial virus (RSV)-A Memphis 37b (Part 4).

Timeline

Start
2018-05-09
Primary completion
2019-11-24
Completion
2019-11-24

Drugs

EvaluationDrugModalityDoseRoute
Subject JNJ-64417184 Unknown 40 mg Oral

Indications

No indication recorded.