drugset
drugset / Trial / NCT03403972

Evaluate the Effects of the Environmental Change in Intestine by Antibiotics on the Pharmacokinetic Characteristics of Simvastatin in Healthy Male Volunteers

NCT03403972 ↗

Phase 1 Completed 6 enrolled Seoul National University Hospital
NaSingle-groupOpen-labelBasic science

Summary

This phase 1 clinical trial is to evaluate the effects of the environmental change in intestine by antibiotics on the pharmacokinetic characteristics of simvastatin in healthy male volunteers. For change of intestine environment, especially the gut microbiota, investigators will administer PO vancomycin for 7 days, tid.

Timeline

Start
2017-12-06
Primary completion
2018-01-11
Completion
2018-01-11

Drugs

EvaluationDrugModalityDoseRoute
Background Vancomycin Other / unclassified 500 mg Oral

Indications

No indication recorded.