drugset / Trial / NCT03406949

MGD009/MGA012 Combination in Relapsed/Refractory Cancer

NCT03406949

Phase 1 Completed 25 enrolled MacroGenics
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics (PK) pharmacodynamics and preliminary antitumor activity of obrindatamab administered in combination with retifanlimab in patients with B7-H3- expressing tumors.

Timeline

Start
2018-02-27
Primary completion
2022-04-27
Completion
2022-04-27

Drugs

EvaluationDrugModalityDoseRoute
Subject MGD009 Protein / enzyme biologic Intravenous
Subject Retifanlimab Monoclonal antibody Intravenous

Indications