drugset / Trial / NCT03410732
Dendritic Cell-based Immunotherapy in Treatment Gastric Cancer
Non-randomizedParallel-groupOpen-labelTreatment
Summary
Study objectives are to investigate the efficacy and safety of activated autologous dendritic cells (DCs) in treatment of gastric cancer. DCs are activated by the proteins from autologous tumor cell membrane and cytokines in vitro. The efficacy endpoints include objective response, immune-cell response, recurrent rate after a radical surgery, progression-free survival and overall survival, and the safety endpoints include adverse events, laboratory tests, ECG, ECOG-PT, etc.
Timeline
- Start
- 2017-07-01
- Primary completion
- 2020-07-01
- Completion
- 2020-12-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | activated DCs | Cell therapy | — | Intravenous |