Mirabegron in Achalasia: A Clinical and Manometric Proof of Concept Pilot Study

Summary

This study evaluates whether a medication called mirabegron is better than placebo (sugar pill) in helping patients with achalasia swallow better. Each patient will receive either mirabegron or the placebo for 4 weeks followed by the opposite medication. Each patient will complete several surveys and undergo several tests to determine if the mirabegron is helping reduce the pressures in the esophagus (swallowing tube).

Timeline

Start

2018-02-15

Primary completion

2019-12-15

Completion

2019-12-15

Drugs

Indications