drugset / Trial / NCT03412799

Study of SBP-101 Combined With Nab-Paclitaxel and Gemcitabine in Pancreatic Cancer

NCT03412799

Phase 1 Completed 50 enrolled Panbela Therapeutics, Inc.
NaSingle-groupOpen-labelTreatment

Summary

This is an open-label phase 1A/1B study to assess the safety, tolerability and pharmacokinetics of SBP-101 when combined with nab-paclitaxel and gemcitabine in subjects with previously untreated metastatic pancreatic ductal adenocarcinoma and to identify a recommended phase 2 dose. The study will also assess preliminary efficacy of the 3-drug treatment combination.

Timeline

Start
2018-06-04
Primary completion
2022-02-28
Completion
2022-02-28

Drugs

EvaluationDrugModalityDoseRoute
Subject IVOSPEMIN Other / unclassified Subcutaneous
Background Gemcitabine Small molecule Intravenous
Background Paclitaxel Small molecule Intravenous