drugset / Trial / NCT03415802

Efficacy and Safety of Nab-Paclitaxel Plus S-1 in the First-line Treatment of Advanced Pancreatic Cancer

NCT03415802 ↗

Phase 2 Completed 32 enrolled Aiping Zhou
NaSingle-groupOpen-labelTreatment

Summary

Pancreatic cancer is a common malignancy of digestive system with gradually increasing incidence, is the fourth and seventh leading cause of cancer-related mortality in the world (1) and China (2) according to the statistics in 2014. The vast majority of patients were confirmed as locally advanced or distantly metastatic disease at diagnosis with an estimated five-year survival rate of 4% (3) due to occlusive development and rapid progress. Advanced pancreatic cancer is characterized by poor prognosis.

Timeline

Start
2015-05-11
Primary completion
2017-07-11
Completion
2019-07-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Nab-paclitaxel Small molecule 120 mg/m2 —
Subject S-1 Small molecule 40 mg Oral
Subject S-1 Small molecule 50 mg Oral
Subject S-1 Small molecule 60 mg Oral

Indications