drugset / Trial / NCT03417141

Valchlor in the Treatment of Lichen Planopilaris

NCT03417141

Phase 2 Completed 12 enrolled Mayo Clinic Actelion · collab
NaSingle-groupOpen-labelTreatment

Summary

The primary objective of this study is to assess the potential effectiveness of once daily application of Valchlor in decreasing disease activity in patients with Lichen Planopilaris. The primary measurement of efficacy will be with the Lichen Planopilaris Activity Index (LPPAI) before and after 6 months of treatment. Secondary measures of efficacy will be the mean follicular density, Physician Global assessment (PGA) score, and the Dermatology Quality of Life Index (DQLI) score before and after six months of therapy.

Timeline

Start
2018-04-01
Primary completion
2019-08-30
Completion
2019-08-30

Drugs

EvaluationDrugModalityDoseRoute
Subject mechlorethamine Small molecule 0.016 % Topical

Indications