drugset / Trial / NCT03418493
A Study of LY3316531 in Healthy Participants and in Participants With Psoriasis
RandomizedParallel-groupDouble-blindBasic science
Summary
The purpose of this study is to evaluate how well LY3316531 is tolerated and what side effects may occur in healthy participants and participants with psoriasis. The study drug will be administered either subcutaneously (SC) (under the skin) or intravenously (IV) (into a vein in the arm). This is a three-part study. Participants will enroll in only one part. Parts A and B are for healthy participants and Part C is for participants with psoriasis. Participation could last between 16 and 57 weeks.
Timeline
- Start
- 2018-01-30
- Primary completion
- 2018-12-24
- Completion
- 2019-07-29
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | LY3316531 | Unknown | 3 mg | Intravenous |
| Subject | LY3316531 | Unknown | 15 mg | Intravenous |
| Subject | LY3316531 | Unknown | 75 mg | Intravenous |
| Subject | LY3316531 | Unknown | 300 mg | Intravenous |
| Subject | LY3316531 | Unknown | 300 mg | Subcutaneous |
| Subject | LY3316531 | Unknown | 900 mg | Intravenous |
| Subject | LY3316531 | Unknown | 2000 mg | Intravenous |