The Effect of Sumatriptan and Placebo Injection on Cilostazol Induced Headache

Summary

To develop a pragmatic migraine model the investigators will induce headache in patients with migraine without aura with a phosphodiesterase inhibitor (cilostazol). If the headache responds to sumatriptan injection, the model can be used to test new drug candidates.

Timeline

Start

2017-11-01

Primary completion

2018-09-01

Completion

2018-09-01

Publications

• Falkenberg K, Bjerg HR, Olesen J. Subcutaneous sumatriptan reduces cilostazol induced headache in migraine patients. Cephalalgia. 2020 Jul;40(8):842-850. doi: 10.1177/0333102420915166. Epub 2020 Mar 26.

Drugs

Indications