Pharmacokinetic Study of Perampanel in Chinese Healthy Subjects

Phase 1 Completed 44 enrolled Eisai Inc.

Non-randomizedParallel-groupOpen-labelBasic science

Summary

This study will be conducted to evaluate the pharmacokinetics of perampanel following single and multiple oral doses in Chinese healthy male and female participants.

Timeline

Start: 2018-03-20
Primary completion: 2018-05-25
Completion: 2018-05-25

Publications

Jing S, Shiba S, Morita M, Yasuda S, Lin Y. A Single- and Multiple-Dose Pharmacokinetic Study of Oral Perampanel in Healthy Chinese Subjects. Clin Drug Investig. 2023 Mar;43(3):155-165. doi: 10.1007/s40261-022-01241-8. Epub 2023 Feb 6.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Perampanel	Small molecule	2 mg	Oral
Subject	Perampanel	Small molecule	4 mg	Oral
Subject	Perampanel	Small molecule	8 mg	Oral

Indications

No indication recorded.