drugset / Trial / NCT03426761
Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections
Phase 4
Completed
41 enrolled
Infectious Diseases Physicians, Inc.
Johns Hopkins University · collab
RandomizedSequentialOpen-labelTreatment
Summary
Because of its prolonged terminal half-life, dalbavancin is an extremely attractive option in treating Gram-positive infections caused by S. aureus including MRSA, and streptococcal species. Systemic bacterial infections due to Staphylococci such as osteomyelitis and septic arthritis, are conditions which require prolonged IV therapy, typically for at least 3-6 weeks, though sometimes more. Due to dalbavancin's prolonged terminal half-life, it may offer the opportunity to substantially reduce costs and morbidity in native joint and prosthetic joint infections with one infusion every fourteen days until completion of therapy.
Timeline
- Start
- 2018-01-25
- Primary completion
- 2022-12-31
- Completion
- 2022-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dalbavancin | Other / unclassified | 1500 mg | Intravenous |
| Comparator | Vancomycin | Other / unclassified | — | Intravenous |