drugset / Trial / NCT03426761

Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections

NCT03426761

RandomizedSequentialOpen-labelTreatment

Summary

Because of its prolonged terminal half-life, dalbavancin is an extremely attractive option in treating Gram-positive infections caused by S. aureus including MRSA, and streptococcal species. Systemic bacterial infections due to Staphylococci such as osteomyelitis and septic arthritis, are conditions which require prolonged IV therapy, typically for at least 3-6 weeks, though sometimes more. Due to dalbavancin's prolonged terminal half-life, it may offer the opportunity to substantially reduce costs and morbidity in native joint and prosthetic joint infections with one infusion every fourteen days until completion of therapy.

Timeline

Start
2018-01-25
Primary completion
2022-12-31
Completion
2022-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Dalbavancin Other / unclassified 1500 mg Intravenous
Comparator Vancomycin Other / unclassified Intravenous