drugset / Trial / NCT03429946
Hypoglycemia and Autonomic Nervous System Function-B
Phase 4
Completed
28 enrolled
Brigham and Women's Hospital
Beth Israel Deaconess Medical Center · collabNational Center for Advancing Translational Sciences (NCATS) · collabNational Heart, Lung, and Blood Institute (NHLBI) · collab
RandomizedCrossoverTriple-blindBasic science
Summary
This study tests the hypothesis that, compared to prior normal blood sugar, prior low blood sugar impairs cardiovascular autonomic function. The proposed studies will also test the hypothesis that the effects of prior low blood sugar on cardiovascular autonomic function are blocked by administration of a mineralocorticoid receptor antagonist.
Timeline
- Start
- 2013-07-17
- Primary completion
- 2025-11-25
- Completion
- 2025-11-25
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Spironolactone | Small molecule | 100 mg | — |