Safety of Autologous Cord Blood Cells in HLHS Patients During Norwood Heart Surgery

Summary

This study aims to evaluate the safety and feasibility of coronary infusion of autologous placental cord blood mononuclear cells during the Norwood heart operation in newborn hypoplastic left heart syndrome (HLHS) patients.

Timeline

Start

2018-02-16

Primary completion

2021-11-01

Completion

2022-06-30

Publications

• Brizard CP, Elwood NJ, Kowalski R, Horton SB, Jones BO, Hutchinson D, Zannino D, Sheridan BJ, Butt W, Cheung MMH, Pepe S. Safety and feasibility of adjunct autologous cord blood stem cell therapy during the Norwood heart operation. J Thorac Cardiovasc Surg. 2023 Dec;166(6):1746-1755. doi: 10.1016/j.jtcvs.2023.07.035. Epub 2023 Jul 30.

Drugs

Indications