drugset / Trial / NCT03432676

Epacadostat and Pembrolizumab in Treating Participants With Advanced Pancreatic Cancer

NCT03432676

NaSingle-groupOpen-labelTreatment

Summary

This phase II trial studies how well epacadostat and pembrolizumab work in treating participants with pancreatic cancer that has spread to other places in the body. Epacadostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving epacadostat and pembrolizumab may work better in treating participants with pancreatic cancer.

Timeline

Start
2019-07-31
Primary completion
2020-04-30
Completion
2021-04-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Epacadostat Small molecule Oral
Subject Pembrolizumab Monoclonal antibody Intravenous