Single-dose Ketamine for the Reduction of Pain and Depression in the Emergency Department

Summary

In this proposal, the investigators will determine if a single dose of intravenous (IV) ketamine (in combination with midazolam) reduces pain severity, depressive symptoms and need for opiate analgesics both in the ED and in the acute recovery period after ED discharge. The investigators will compare the ketamine arm to an active placebo-controlled arm (with midazolam).

Timeline

Start

2019-12

Primary completion

2020-02-05

Completion

2020-02-05

Drugs

Indications