drugset / Trial / NCT03437005

Alternation in the Human Microbiome With Commonly Used Topical Medications

NCT03437005

Phase 1 Recruiting 24 enrolled University of California, Davis
RandomizedParallel-groupDouble-blindBasic science

Summary

The global aim of this study is to investigate how the human microbiome changes from baseline with commonly used topical medications such as topical antifungals, low to mid potency topical steroids and emollients. The specific aims are as follows: 1. Investigate whether ketoconazole cream, a commonly used topical antifungal, causes alterations in the human skin microbiome with short-term use. 2. Investigate whether desonide 0.05 % ointment, a commonly used low potency topical steroid, alters the human microbiome with short-term use.

Timeline

Start
2013-01-28
Primary completion
2026-09-28
Completion
2026-09-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Desonide Small molecule 0.05 % Topical
Subject Ketoconazole Small molecule 2 % Topical

Indications

No indication recorded.