Fluorescence QRH-882260 Peptide Imaging in the Bile Duct

Summary

Patients undergoing ERCP procedure with biliary stricture will have epithelial mucosa labeled with QRH-882260 fluorescence peptide that binds to EGFR. A custom mini-cholangioscope will be used to image the luminal surfaces of the biliary duct that are exposed to the fluorescence peptide. The images will be recorded and analyzed for relative fluorescence pattern and intensity and correlated to patient diagnosis and clinical outcomes.

Timeline

Start

2019-04-22

Primary completion

2020-08-21

Completion

2020-08-21

Drugs

Indications