drugset / Trial / NCT03439215
PF-06463922 for Crizotinib Pretreated ROS1 Positive Non-small-cell Lung Cancer
Phase 2
Unknown
20 enrolled
Fondazione Ricerca Traslazionale
Clinical Research Technology S.r.l. · collab
NaSingle-groupOpen-labelTreatment
Summary
This is a phase II study assessing response rate to PF-06463922 in patients with ROS1 translocation resistant to previous crizotinib therapy. Eligible patients will be treated with the study drug until disease progression, unacceptable toxicity or patient refusal. Disease assessment will be performed every 8 weeks according to RECIST criteria.
Timeline
- Start
- 2017-06-13
- Primary completion
- 2022-06
- Completion
- 2022-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lorlatinib | Small molecule | 100 mg | Oral |