drugset / Trial / NCT03439215

PF-06463922 for Crizotinib Pretreated ROS1 Positive Non-small-cell Lung Cancer

NCT03439215

NaSingle-groupOpen-labelTreatment

Summary

This is a phase II study assessing response rate to PF-06463922 in patients with ROS1 translocation resistant to previous crizotinib therapy. Eligible patients will be treated with the study drug until disease progression, unacceptable toxicity or patient refusal. Disease assessment will be performed every 8 weeks according to RECIST criteria.

Timeline

Start
2017-06-13
Primary completion
2022-06
Completion
2022-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Lorlatinib Small molecule 100 mg Oral