drugset / Trial / NCT03439254

Study Evaluating the Efficacy and Safety of Obeticholic Acid in Subjects With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis

NCT03439254

Phase 3 Completed 919 enrolled Intercept Pharmaceuticals
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The primary objective of this study is to evaluate whether obeticholic acid (OCA; INT-747) can lead to histological improvement in fibrosis with no worsening of NASH in adults with compensated cirrhosis due to NASH.

Timeline

Start
2017-08-30
Primary completion
2022-09-08
Completion
2022-09-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Obeticholic Acid Small molecule 10 mg Oral
Subject Obeticholic Acid Small molecule 25 mg Oral