Fecal Transplant for Hepatic Encephalopathy

Summary

The purpose of the study is to determine if fecal microbiota transplant (FMT) can reverse hepatic encephalopathy (HE) in cirrhotic patients who continue to have breakthrough episodes of HE despite maintenance therapy with lactulose and/or rifaximin or metronidazole.

Timeline

Start

2016-04-12

Primary completion

2019-08-07

Completion

2021-03-18

Publications

• Pun CK, Huang HC, Chang CC, Hsu SJ, Huang YH, Hou MC, Lee FY. Hepatic encephalopathy: From novel pathogenesis mechanism to emerging treatments. J Chin Med Assoc. 2024 Mar 1;87(3):245-251. doi: 10.1097/JCMA.0000000000001041. Epub 2023 Dec 18.

Drugs

Indications