drugset / Trial / NCT03443414

Dose Ranging Study of RPL554 in Chronic Obstructive Pulmonary Disease (COPD) Patients

NCT03443414

Phase 2 Completed 405 enrolled Verona Pharma, Inc.
RandomizedParallel-groupDouble-blindTreatment

Summary

The study investigates the effect of 4 weeks of twice daily treatment of four different doses of RPL554 (a phosphodiesterase \[PDE\]3/4 inhibitor) or placebo in patients with moderate to severe chronic obstructive pulmonary disease (COPD). Patients will be equally allocated to one of the five treatment options.

Timeline

Start
2017-06-01
Primary completion
2018-01-23
Completion
2018-02-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Ensifentrine Unknown 0.75 mg Inhaled
Subject Ensifentrine Unknown 1.5 mg Inhaled
Subject Ensifentrine Unknown 3 mg Inhaled
Subject Ensifentrine Unknown 6 mg Inhaled