drugset / Trial / NCT03443414
Dose Ranging Study of RPL554 in Chronic Obstructive Pulmonary Disease (COPD) Patients
RandomizedParallel-groupDouble-blindTreatment
Summary
The study investigates the effect of 4 weeks of twice daily treatment of four different doses of RPL554 (a phosphodiesterase \[PDE\]3/4 inhibitor) or placebo in patients with moderate to severe chronic obstructive pulmonary disease (COPD). Patients will be equally allocated to one of the five treatment options.
Timeline
- Start
- 2017-06-01
- Primary completion
- 2018-01-23
- Completion
- 2018-02-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ensifentrine | Unknown | 0.75 mg | Inhaled |
| Subject | Ensifentrine | Unknown | 1.5 mg | Inhaled |
| Subject | Ensifentrine | Unknown | 3 mg | Inhaled |
| Subject | Ensifentrine | Unknown | 6 mg | Inhaled |