drugset / Trial / NCT03448042

A Study of Runimotamab in Participants With Locally Advanced or Metastatic HER2-Expressing Cancers

NCT03448042

Phase 1 Active not recruiting 123 enrolled Genentech, Inc.
Non-randomizedSequentialOpen-labelTreatment

Summary

This study will evaluate the safety, tolerability, and pharmacokinetics of Runimotamab administered intravenously as a single agent and in combination with Trastuzumab in participants with locally advanced or metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-expressing cancers.

Timeline

Start
2018-06-06
Primary completion
2027-11-30
Completion
2027-11-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Runimotamab Monoclonal antibody Intravenous
Subject Trastuzumab Monoclonal antibody Intravenous
Background Tocilizumab Monoclonal antibody Intravenous

Indications