drugset / Trial / NCT03450083
Benralizumab Effect on Severe Chronic Rhinosinusitis With Eosinophilic Polyposis
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Benralizumab will be used in a placebo controlled randomized study to treat severe chronic rhinosinusitis with nasal polyps
Timeline
- Start
- 2017-07-01
- Primary completion
- 2020-01-01
- Completion
- 2020-02-01
Publications
- Geng B, Dilley M, Anterasian C. Biologic Therapies for Allergic Rhinitis and Nasal Polyposis. Curr Allergy Asthma Rep. 2021 Jun 10;21(6):36. doi: 10.1007/s11882-021-01013-y.
- Tversky J, Lane AP, Azar A. Benralizumab effect on severe chronic rhinosinusitis with nasal polyps (CRSwNP): A randomized double-blind placebo-controlled trial. Clin Exp Allergy. 2021 Jun;51(6):836-844. doi: 10.1111/cea.13852. Epub 2021 Feb 27.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Benralizumab | Monoclonal antibody | 30 mg | Subcutaneous |