drugset

drugset / Trial / NCT03452111

Study of Daily Application of Nestorone® (NES) and Testosterone (T) Combination Gel for Male Contraception

NCT03452111 ↗

Phase 2 Completed 420 enrolled Premier Research Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · collab Population Council · collab

NaSingle-groupOpen-labelOther

Summary

The long term objective is to develop a gel to be used as a male contraceptive.

Timeline

Start: 2018-10-25
Primary completion: 2024-09-06
Completion: 2024-09-06

Publications

Lue Y, Swerdloff R, Pak Y, Nguyen BT, Yuen F, Liu PY, Blithe DL, Wang C. Male contraception development: monitoring effective spermatogenesis suppression utilizing a user-controlled sperm concentration test compared with standard semen analysis. Fertil Steril. 2023 Feb;119(2):208-217. doi: 10.1016/j.fertnstert.2022.11.002. Epub 2022 Nov 5.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Segesterone Acetate	Small molecule	—	Other
Subject	Testosterone	Small molecule	62 mg	Other
Subject	Testosterone	Small molecule	74 mg	Other

Indications

No indication recorded.