drugset / Trial / NCT03452566

Evaluation of Ingenol Mebutate for Actinic Cheilitis Treatment

NCT03452566

NaSingle-groupOpen-labelTreatment

Summary

Actinic cheilitis is a major potentially carcinogenic disorder of the lower lip and several reports of clinical cases with excellent results for the treatment of this lesion that can differentiate to squamous cell carcinoma of the lip. However, clinical trials are lacking to define the optimal dosage of the drug for a therapeutic modality and to define its true efficacy in controlled studies of this pre-malignant labial lesion.

Timeline

Start
2020-02
Primary completion
2021-09
Completion
2022-04

Drugs

EvaluationDrugModalityDoseRoute
Subject ingenol mebutate Small molecule 5 mg/m2
Subject ingenol mebutate Small molecule 18 mg/m2

Indications