drugset / Trial / NCT03452566
Evaluation of Ingenol Mebutate for Actinic Cheilitis Treatment
NaSingle-groupOpen-labelTreatment
Summary
Actinic cheilitis is a major potentially carcinogenic disorder of the lower lip and several reports of clinical cases with excellent results for the treatment of this lesion that can differentiate to squamous cell carcinoma of the lip. However, clinical trials are lacking to define the optimal dosage of the drug for a therapeutic modality and to define its true efficacy in controlled studies of this pre-malignant labial lesion.
Timeline
- Start
- 2020-02
- Primary completion
- 2021-09
- Completion
- 2022-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ingenol mebutate | Small molecule | 5 mg/m2 | — |
| Subject | ingenol mebutate | Small molecule | 18 mg/m2 | — |